Clinical utility of rotational thromboelastometry in detecting hemostatic disorders

Hemostatic management in complex aortic surgery: a role for multiple electrode aggregometry and modified rotational thromboelastometry.

Clinical and laboratorial description of the differential diagnoses of hemostatic disorders in the horse

The process of fibrin clot formation is a series of complex and well-regulated reactions involving blood vessels, platelets, procoagulant plasma proteins, natural inhibitors, and fibrinolytic enzymes. Vasculitis can be caused by a variety of different agents as bacteria, viruses, protozoal, rickettsial organisms, toxic, drugs, medications, and neoplasms. The most common cause of vasculitis is t...

Hemostatic disorders in women.

The past few decades have seen major advances in multidisciplinary obstetric care and management of gynecological conditions in women with bleeding disorders. Awareness of the impact of bleeding disorders has improved among the obstetric and gynecological community. Undiagnosed bleeding disorders can be the underlying cause for a significant proportion of women with heavy menstrual bleeding. Th...

Thrombin generation and rotational thromboelastometry in the healthy adult population.

AIM Published data on thrombin generation variables and their correlation with thromboelastometry in the healthy population are scarce. This study aimed at assessing thrombin generation in adults and its correlation to classical rotational thromboelastometry (ROTEM). METHODS Thrombin generation was measured in platelet-poor plasma from healthy volunteers using the calibrated automated thrombo...

Reference ranges for rotational thromboelastometry in male Sprague Dawley rats

Background A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system. Methods Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM® delta hemostasis analyzer with the EXTEM test. Res...